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Product Name |
ThankGod Anytime Cream™ |
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Composition |
Each gram contains:
- Purified Euphorbia
prostrata Extract 10 mg
- Cream base qs
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Introduction |
Euphorbia prostrata is a
common herb found all over India especially in foot
hills of Himalayas. The extract of Euphorbia prostrata
has been found to have significant anti-inflammatory,
analgesic, haemostatic (stops bleeding) and wound
healing properties. Preclinical and clinical trials have
demonstrated its efficacy as an anti-hemorrhoid agent.
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Pharmacology |
The major flavonoid
components of Euphorbia prostrata Extract are Apigenin,
Luteolin, Apigenin-7-glucoside and Luteolin-7-glucoside.
The major phenolic compounds present are Gallic acid,
Ellagic acid and Tannins.
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Actions and effects |
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- Anti-hemorrhoidal
activity : Euphorbia prostrata Extract has been
clearly shown to have significant anti-hemorrhoidal
activity as demonstrated by ano-rectal body: weight
ratio model in rats.
- Anti-inflammatory
activity : Various components of Euphorbia
prostrata Extract are known to affect inflammatory
response to antigen. Apigenin-7-glucoside inhibits
release of histamine, generation of hydrogen peroxide
and leucocyte infiltration at inflammatory site.
Luteolin-7-glucoside decreases leucocyte infiltration.
- Analgesic activity
: Analgesic activity of Euphorbia prostrata
Extract may be ascribed to inhibition of exudates
formation and migration of neutrophils and monocytes.
- Haemostatic
activity : Euphorbia prostrata Extract on topical
application significantly reduced the bleeding time.
This effect could play an important role in arrest of
bleeding.
- Wound healing
effect : Topical application of Euphorbia
prostrata Extract has been shown to have significant
wound healing effect.
- Vasoprotective
activity : Flavonoids tend to decrease capillary
permeability and increase capillary resistance.
Several mechanisms have been proposed such as
inhibition of ascorbic acid oxidation, blood cell
aggregation and stimulation of pituitary-adrenal axis.
- Anti-allergic
activity : Apigenin and Luteolin inhibit basophil
histamine release and neutrophil beta glucoronidase
release, thus exerting anti-allergic effects.
- Sclerosing activity
: Tannins present in Euphorbia prostrata Extract
cause sclerosis of the mucus membrane by virtue of
their protein precipitating property.
- Anti-oxidant
activity : Flavonoids and Phenolic compounds of
the extract have anti-oxidant property which also
contributes in healing of inflammatory tissue damage
in hemorrhoidal conditions.
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Indications |
ThankGod Anytime Cream™ is
intended to relieve bleeding, pain, anal discomfort and
inflammation in hemorrhoids or piles (especially first
and second degree hemorrhoids).
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Dosage |
Apply locally morning,
evening and after each evacuation or as per medical
advice.
FOR EXTERNAL USE ONLY. Keep out of reach of children.
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Precautions |
Stop use and consult your
physician if bleeding is excessive/ if the bleeding
persists/ if there is passage of black tarry stools/ if
there is seepage or protrusion in the anal area
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Contraindications |
Not recommended in children,
during pregnancy and breast feeding, if allergic to any
of the ingredients and in patients on anticoagulant
therapy
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Adverse effects |
Not known
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Storage |
Store in a cool and dry
place, away from direct sunlight. Do not refrigerate. |
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Supply |
ThankGod Anytime Cream™ is
supplied in a 30 gram tube with applicator.
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Proprietary Ayurvedic
Medicine |
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