Product Information - ThankGod Relief Capsules*

Product Name ThankGod Relief Capsules™
Composition Each hard gelatin capsule contains Euphorbia prostrata Extract 100 mg.
Introduction Euphorbia prostrata is a common herb found all over India especially in foot hills of Himalayas. The extract of Euphorbia prostrata has been found to have significant anti-inflammatory, analgesic, haemostatic and wound healing properties. Preclinical and clinical trials have demonstrated its efficacy as an anti-hemorrhoid agent.
 
Pharmacology The major flavonoid components of Euphorbia prostrata Extract are Apigenin, Luteolin, Apigenin-7-glucoside and Luteolin-7-glucoside. The major phenolic compounds present are Gallic acid, Ellagic acid and Tannins.
 
Actions and effects  
  • Anti-oxidant activity :Flavonoids and phenolic compounds of the extract have anti-oxidant property which also contributes in healing of inflammatory tissue damage in hemorrhoidal conditions.
  • Anti-hemorrhoidal activity: Euphorbia prostrata Extract has been shown to have significant anti-hemorrhoidal activity as demonstrated by ano-rectal weight: body weight ratio model in rats.
  • Anti-inflammatory activity: Various components of Euphorbia prostrata Extract are known to affect inflammatory response to antigens. Apigenin-7-glucoside inhibits release of histamine, generation of hydrogen peroxide and leucocyte infiltration at inflammatory site. Luteolin-7-glucoside decreases leucocyte infiltration.
  • Analgesic activity: Analgesic activity of Euphorbia prostrata Extract may be ascribed to inhibition of exudates formation and migration of neutrophils and monocytes.
  • Haemostatic activity: Flavonoids have a significant effect on in terms of rapid cessation of bleeding and reduced risk of relapse in Piles (hemorrhoids).
  • Vasoprotective activity: Flavonoids tend to decrease capillary permeability and increase capillary resistance. Several mechanisms have been proposed such as inhibition of ascorbic acid oxidation, blood cell aggregation and stimulation of pituitary-adrenal axis.
  • Anti-allergic activity: Apigenin and Luteolin inhibit basophil histamine release and neutrophil beta glucoronidase release, thus exerting anti-allergic effects.
 
 
Indications ThankGod Relief Capsules™ are intended for long term relief from bleeding, pain, anal discomfort and inflammation in hemorrhoids (especially first and second degree hemorrhoids).
 
Dosage One capsule daily in the morning on empty stomach. Do not exceed the recommended doses. Keep out of reach of children.
 
Precautions Stop use and consult your physician if bleeding is excessive/ if the bleeding persists/ if there is passage of black tarry stools/ if there is seepage or protrusion in the anal area.
 
Caution The safety of ThankGod Relief Capsules™ has not been established in pregnant, lactating mothers, in children and in patients on anticoagulant therapy.
 
Adverse effects The drug is usually well tolerated. However, nausea, dyspepsia, abdominal pain, diarrhea, headache and dry mouth have been reported in some cases.
 
Drug interactions Not known
Overdosage Consult the Physician immediately
Storage Store in a cool and dry place away from direct sunlight and moisture
Supply ThankGod Relief Capsules™ are supplied in a “mooda” shaped plastic bottle containing 14 capsules and in a blister pack of 7 capsules

 

Proprietary Ayurvedic Medicine

* based upon the stability data of ThankGodTM Capsules & Tablets it was observed that the stability profile of the tablets was found to be better than capsules, hence finished dosage form has now been changed to tablets

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